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LNA: locked nucleic acid. Try to use the link:
https://en.wikipedia.org/wiki/Locked_nucleic_acid
for more details.
LNA is nothing to do luciferase assay. miR-LNA indicates micRNA is synthesized with LNA modification. In the figure, C is a result to normalize different synthesized microRNA or negative control (NC) exprerssion in testing cell lines, such as BT549, etc. D, a kind of result of luciferase assay upon different micRNA or NC transfection.