增光霉素(博来霉素)别名:争光霉素Zeocin

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单价: 2000.00
品牌: invivogen
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更新: 2020-08-03
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货号: ant-zn-1
供应商: 上海研卉生物科技有限公司
数量: 大量
英文名: Zeocin™ Selection Antibiotic
规格: 10*1ml
博来霉素优惠促销
Zeocin™ Selection Antibiotic (100 mg/mL)
描述
博来霉素报价
100 mg⁄ml
Regulatory Statement:     
增光霉素(博来霉素)别名:争光霉素Zeocin

Selection antibiotic: cell culture tested, sterile reagent

InvivoGen is the sole worldwide producer of Zeocin™, a popular and effective antibiotic for the selection of vectors bearing the Sh ble gene in a variety of cells types (bacteria, eukaryotic microorganisms, plant and animal cells).

Resistance to Zeocin™ is conferred by the Sh ble gene product, which inactivates Zeocin™ by binding to the antibiotic. Sh ble is a small gene, only 370bp in size, carried in a number of InvivoGen’s vectors.

Zeocin™ is a copper-chelated glycopeptide antibiotic produced by Streptomyces CL990. Zeocin™ causes cell death by intercalating into DNA and cleaving it. The action of Zeocin™ is effective on most aerobic cells.

Typically, mammalian cells are sensitive to Zeocin™ concentrations of 50-400 µg/ml, and bacteria to 25 µg/ml.

Product concentration: 100 mg/ml in solution
CAS number: 11006-33-0

Quality Control: Each lot is thoroughly tested to ensure the absence of lot-to-lot variation.
Endotoxin level: < 1 EU/mg
Physicochemical characterization: HPLC, pH, appearance
Cell-culture tested: potency validated in Zeocin™-sensitive and Zeocin™-resistant mammalian cell lines
Non-cytotoxicity of trace contaminants: absence of long-term effects confirmed in Zeocin™-resistant cells

Zeocin™ is supplied as a sterile filtered blue solution at 100 mg/ml in HEPES buffer. This product is available in three pack sizes:
- ant-zn-1: 10 x 1 ml (1 g)
- ant-zn-5: 50 x 1 ml (5 g)
- ant-zn-5b: 1 x 50 ml (5 g)

Zeocin™ is also supplied as a blue powder:
- ant-zn-1p: 1 x 1 g

Recent articles using InvivoGen Zeocin™

 

 

  • 2017 - Nature., 543(7646):568-572.
    DND1 maintains germline stem cells via recruitment of the CCR4–NOT complex to target mRNAs.
    Yamaji M. et al.
  • 2017 - Cell., 168(3):503-516.
    Pathogen-Mediated Inhibition of Anorexia Promotes Host Survival and Transmission.
    Rao S. et al.
  • 2017 - Nat Commun., 8:14391.
    IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP.
    Jønsson KL. et al.
  • 2017 - Sci Rep., 7:44328.
    Plectin is a novel regulator for apical extrusion of RasV12-transformed cells
    Kadeer A. et al.
  • 2017 - PNAS, [Epub ahead of print]
    Rational design of adjuvants targeting the C-type lectin Mincle.
    Decout A. et al.


For Research Use Only. Not for use in diagnostic procedures.
上海研卉生物科技有限公司 ,是一家专注于生命科学和生物技术领域的高科技企业,专业提供分子生物学、免疫学、生命科学基础研究以及临床检测等诸多领域的试剂、耗材、仪器等各类产品及生物技术服务。公司主营业务: 试剂盒:酶联免疫试剂盒、免疫印迹试剂盒、免疫组化试剂盒、细胞凋亡检测试剂盒、分子生物学试剂盒。 细胞:原装进口细胞、国产肿瘤细胞、国产正常细胞。 耗材:细胞培养耗材、普通实验耗材。 生化试剂:原装进口生化试剂、进口分装生化试剂、国产生化试剂。 抗体:免疫组化、免疫荧光、流式细胞检测、免疫细胞化学。
温馨提示:不可用于临床治疗。