Anti-Relaxin 3抗体

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单价: 1380.00
品牌: Ybscience
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更新: 2020-10-14
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 Anti-Relaxin 3抗体

产品编号 YB-11412R
英文名称 Relaxin 3
中文名称 松弛素3抗体
别    名 H3; INSL 7; INSL7; *** like 7; *** like peptide 7; *** like peptide INSL7; *** like7; ***like 7; Prorelaxin H3; Prorelaxin M3; REL 3; REL3; Relaxin 3; Relaxin 3 (H3); Relaxin 3 A chain; Relaxin 3 precursor; Relaxin3; RLN 3; RLN3; RXN 3; RXN3; ZINS 4; ZINS4; REL3_HUMAN.  
规格价格 100ul/1380元 购买    200ul/2200元 购买    大包装/询价
说 明 书 100ul  200ul
研究领域 肿瘤  细胞生物  发育生物学  神经生物学  信号转导  生长因子和***  
抗体来源 Rabbit
克隆类型 Polyclonal
交叉反应 Human, Mouse, Rat, 
产品应用 IHC-P=1:400-800 IHC-F=1:400-800 (石蜡切片需做抗原修复)  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量 3kDa
细胞定位 分泌型蛋白 
性    状 Lyophilized or Liquid
浓    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Relaxin 3 A chain:119-135/142 
亚    型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
PubMed PubMed
产品介绍 background: Relaxins are known endocrine and autocrine/paracrine hormones, belonging to the insulin gene superfamily. In the human there are three non allelic relaxin genes, RLN1, RLN2 and RLN3. RLN1 and RLN2 share high sequence homology. Relaxin is produced by the ovary, and targets the mammalian reproductive system to ripen the cervix, elongate the pubic symphysis and inhibit uterine contraction. It may have additional roles in enhancing sperm motility, regulating blood pressure, controlling heart rate and releasing oxytocin and vasopressin. The protein encoded by this gene is a member of the relaxin family. The active form of the encoded protein consists of an A chain and a B chain but their cleavage sites are not definitely described yet. It may play a role in neuropeptide signaling processes. Function: May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142). Subunit: Heterodimer of a B chain and an A chain linked by two disulfide bonds. Subcellular Location: Secreted. Similarity: Belongs to the insulin family. SWISS: Q8WXF3 Gene ID: 117579 Database links:

Entrez Gene: 117579 Human

Omim: 606855 Human

SwissProt: Q8WXF3 Human

Unigene: 352155 Human

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.   
产品图片
Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;  Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;  Incubation: Anti-Relaxin-3 Polyclonal Antibody, Unconjugated(bs-11412R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining