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Rabbit Anti-Cecropin antibody
| 产品编号 | hz-2080R |
| 英文名称 | Cecropin |
| 中文名称 | 抗菌肽/天蚕素抗体 |
| 产品类型 | 植物抗体 |
| 研究领域 | 细菌及病毒 植物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Hyalophora cecropia |
| 产品应用 | ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 IF=1:100-500 （石蜡切片需做抗原修复） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 4kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide from Hyalophora cecropia Cecropin:1-37/41 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| PubMed | PubMed |
| 产品介绍 | background: Cecropins are antimicrobial peptides.They were first isolated from the hemolymph of Hyalophora cecropia, from whence the term cecropin was derived. Cecropins lyse bacterial cell membranes; they also inhibit proline uptake and cause leaky membranes. Cecropins constitute a main part of the cell-free immunity of insects. Cecropins are small proteins of about 31 - 37 amino acid residues active against both Gram-positive and Gram-negative bacteria. Cecropins isolated from insects other than Hyalophora cecropia (Cecropia moth) have been given various names; bactericidin, lepidopteran, sarcotoxin, etc. All of these peptides are structurally related. Cecropin P1, an intestinal antibacterial peptide from Sus scrofa (Pig), also belongs to this family. Cecropin family also consists Cecropin A and Cecropin B. Function: Cecropins have lytic and antibacterial activity against several Gram-positive and Gram-negative bacteria. Subcellular Location: Secreted. Post-translational modifications: A protein with the same sequence as cecropin A, but lacking the carboxyl blocking group, has been isolated and called cecropin C (PubMed:7140755). Similarity: Belongs to the cecropin family. SWISS: N/A Gene ID: N/A Database links: Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Cecropin抗菌肽又称天蚕素，具有抗菌、抗病毒、抗肿瘤等活性，因其水溶性好，耐高温，是一种比较理想的抗生素代用品；尤其是其主要抑菌机制,可破坏细胞膜的稳定性，不易产生耐药性。 抗菌肽一般是小肽，可以被动物完全消化，不存在残留性的问题，所以，抗菌肽无论是作为饲料添加剂，兽药还是人药，都有理论上的研究价值和生产中的实际意义。 |
