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- Specification
- Product Description:
- Made to order FISH probes for identification of gene amplification using Fluorescent In Situ Hybridization Technique. (Technology)
- Storage Instruction:
- Store at 4°C in the dark.
- Supplied Product:
- DAPI Counterstain (1500 ng/mL ) 250 uL
- Origin:
- Human
- Source:
- Genomic DNA
- Notice:
- We strongly recommend the customer to use FFPE FISH PreTreatment Kit 1 (Catalog #: KA2375 or KA2691) for the pretreatment of Formalin-Fixed Paraffin-Embedded (FFPE) tissue sections.
- Regulation Status:
- For research use only (RUO)
- Applications
- Fluorescent In Situ Hybridization (Cell)
- Protocol Download
- Application Image
- Fluorescent In Situ Hybridization (Cell)
- Gene Information
- Entrez GeneID:
- 6790
- Gene Name:
- AURKA
- Gene Alias:
- AIK,ARK1,AURA,AURORA2,BTAK,MGC34538,STK15,STK6,STK7
- Gene Description:
- aurora kinase A
- Omim ID:
- 114500, 603072
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
- Other Designations:
- IPL1-related kinase,OTTHUMP00000031340,OTTHUMP00000031342,OTTHUMP00000031343,OTTHUMP00000031344,OTTHUMP00000031345,OTTHUMP00000166071,aurora-A,aurora-related kinase 1,aurora/IPL1-like kinase,breast-tumor-amplified kinase,serine/threonine kinase 15,serine/
- Related Disease
- Adenocarcinoma
- Body Weight
- Breast cancer
- Breast Neoplasms
- Carcinoma
- Carcinoma, Ductal, Breast
- Carcinoma, Hepatocellular
- Carcinoma, Medullary
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Renal Cell
- Carcinoma, Squamous Cell
- Chromosome Aberrations
- Colonic Neoplasms
- Colorectal Neoplasms
- Colorectal Neoplasms, Hereditary Nonpolyposis
- Disease Progression
- Esophageal Neoplasms
- Genetic Predisposition to Disease
- Genomic Instability
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