IL-15 (mutant) (human):Fc (human) (rec.)

点击图片查看原图
单价: 0.00
品牌: 未填写
销量: 累计出售 0
评价: 已有 0 条评价
人气: 已有 166 人关注
更新: 2021-05-24
该商品库存不足
看了又看 更多>
 
 
Synonyms :  Interleukin-15Host :  CHO cellSequence :  The extracellular domain of human IL-15(NP_751914.1)(Asn49-Ser162)including mutations at Q149D and Q156D is fused to the N-terminus of the Fc region of human IgG1.Molecular Mass :  41 KDa (monomer)Purity :  >98%,by SDS-PAGE under reducing conditions. Endotoxin Content :  <0.06 EU/μg as determined by LAL test.Activity :  This mutant IL-15/Fc fusion protein specifically binds to the IL-15R, competitively inhibits IL-15-triggered cell  proliferation, promotes transplant tolerance, does not activate the STAT -signaling pathway, and exerts a prolonged circulating half-life caused by the modified Fc domain. Formulation :  Lyophilized from 0.2μm-filtered solution in PBS.Reconstitution :  Reconstitute at 100μg/ml in sterile PBS.Use / Stability :Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.Avoid freeze/thaw cycles.