CD152 [CTLA-4] (human):Fc (human) (rec.)

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Synonyms :  CTLA-4 Host :  CHO cell Sequence :  The extracellular domain of human CD152[CTLA-4](NP_005205.2)(Ala37-Ser160) is fused to the N-terminus of the Fc region of human IgG1. Molecular Mass :  39 KDa (monomer) Purity :  >98%,by SDS-PAGE under reducing conditions.  Endotoxin Content :  <0.06 EU/μg as determined by LAL test. Activity :  Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells.  Formulation :  Lyophilized from 0.2μm-filtered solution in PBS. Reconstitution :  Reconstitute at 100μg/ml in sterile PBS. Use / Stability :  Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for upto 3 months when stored at -20°C.Avoid freeze/thaw cycles.