货号: | ab120286 |
CAS号: | 67526-95-8 |
英文名: | Thapsigargin |
保质期: | 12个月 |
保存条件: | Store at -20°C |
规格: | 1 mg |
概述
- 产品名称
Thapsigargin - 描述
Ca2+-ATPase inhibitor - 生物学描述
A potent, cell-permeable Ca2+-ATPase inhibitor. Releases Ca2+ by inhibiting endoplasmic reticular Ca2+-ATPase (IC50 = 4-13 nM). Both tumorogenic and apoptotic actions reported. - 纯度
> 98%
性能
- 化学名称
(3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(Acetyloxy)-2,3,3a,4,5,6,6a,7,8,9b-decahydro-3,3a-dihydroxy-3,6,9-trimethyl-8-[[(2Z)-2-methyl-1-oxo-2-butenyl]oxy]-2-oxo-4-(1-oxobutoxy)azuleno[4,5-b]furan-7-yl octanoate - 分子量
650.76 - 化学结构
- 分子式
C34H50O12 - CAS编号
67526-95-8 - PubChem识别号
446378 - 存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. - 溶解度概述
Soluble in DMSO to 100 mM - 处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- SMILES
CC=C(C)C(=O)O[C@@H]3[C@@H](OC(=O)CCCCCCC)[C@H]1C([C@@H]2OC(=O)[C@](O)(C)[C@@]2(O)[C@H](C[C@]1(C)OC(C)=O)OC(=O)CCC)=C3C - 来源
Thapsia garganica
温馨提示:不可用于临床治疗。