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| 货号： | ab171268 |
| 规格： | 100 µg |
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| 温馨提示：不可用于临床治疗。 |
温馨提示：不可用于临床治疗。
| 货号： | ab171268 |
| 规格： | 100 µg |
| 描述： | Rat monoclonal [RM4-5] to CD4 - Low endotoxin, Azide free |
| 形态： | Liquid |
| 保存条件： | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
| 纯度： | Protein G purified |
| 克隆性： | 否 |
| 克隆号： | RM4-5 |
| 亚型： | IgG2a |
| 轻链类型： | kappa |
| 功能： | Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation. Induces the aggregation of lipid rafts. |
| 胞内定位： | Cell membrane. Localizes to lipid rafts. Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum. |
| 浓度： | 100 µg at 1 mg/ml |
| 宿主： | Rat |
| 靶点： | CD4 |
| 测试型应用： | Functional Studies , Flow Cyt more details |
| 免疫原： | <p>The details of the immunogen for this antibody are not available. corresponding to CD4.</p> |
| 阳性对照： |
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| 序列相似性： | Contains 3 Ig-like C2-type (immunoglobulin-like) domains. Contains 1 Ig-like V-type (immunoglobulin-like) domain. |
| 数据库链接： |
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| 别名： |
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| 应用范围： | {"Flow Cyt":"\n Flow Cyt: Use 0.5µg for 10\n \n<sup>5-8</sup>\n\n cells.\n \n<p>A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 µL.</p>\n\n\n","Functional Studies":"FuncS: Use at an assay dependent concentration."} |
| 品牌： | abcam |
| 规格： | 100 µg |
|
| 温馨提示：不可用于临床治疗。 |
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