- 英文名称:Deoxynivalenol
- 分子式:C15H20O6
- 分子量:296.32
- EINECS 编号:200-835-2
- MDL Number:MFCD09039270
- 所属类型:生化试剂
- 别名:脱氧瓜萎镰菌醇、呕吐毒素、3Α,7Α,15-三羟基-12,13-环氧单端孢霉-9-蒽-8-酮
- 用途
Deoxynivalenol is a tricothecene mycotoxin and potent protein synthesis inhibitor. Deoxynivalenol exhibits cytotoxic activity in vivo via the ribotoxic stress response. Deoxynivalenol induces p38-medi ated gene expression and apoptosis in leukocytes; activity results in systemic expression of interleukin-6 (IL-6) and other proinflammatory cytokines. Also induces migration of NF-B into the nucleus. |