Anti-TBL1XR1 Polyclonal Antibody

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单价: 960.00
品牌: 江蓝纯
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更新: 2021-05-18
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货号: K005495P
供应商: 江蓝纯
数量: 99
规格: 50ul/100ul
英文名称 Rabbit TBL1XR1 Polyclonal Antibody
应用 WB,IHC,IF
稀释比例 WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:100
交叉反应 Human,Mouse,Rat
蛋白分子量 56kDa
Gene ID 79718
保存 Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment.
储存液 PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG
免疫原 Recombinant protein of human TBL1XR1
性状 Lyophilized or Liquid
Swiss Prot Q9BZK7
克隆类型 Polyclonal Antibody
来源 Rabbit
背景资料 This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors.
温馨提示:不可用于临床治疗。