英文名称 | Rabbit TBL1XR1 Polyclonal Antibody |
应用 | WB,IHC,IF |
稀释比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:100 |
交叉反应 | Human,Mouse,Rat |
蛋白分子量 | 56kDa |
Gene ID | 79718 |
保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human TBL1XR1 |
性状 | Lyophilized or Liquid |
Swiss Prot | Q9BZK7 |
克隆类型 | Polyclonal Antibody |
来源 | Rabbit |
背景资料 | This gene is a member of the WD40 repeat-containing gene family and shares sequence similarity with transducin (beta)-like 1X-linked (TBL1X). The protein encoded by this gene is thought to be a component of both nuclear receptor corepressor (N-CoR) and histone deacetylase 3 (HDAC 3) complexes, and is required for transcriptional activation by a variety of transcription factors. Mutations in these gene have been associated with some autism spectrum disorders, and one finding suggests that haploinsufficiency of this gene may be a cause of intellectual disability with dysmorphism. Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors. |