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| 货号： | EI-SM-034 |
| CAS号： | 详询 |
| 供应商： | 医诺生物 |
| 数量： | 大量 |
| 保质期： | 详询 |
| 保存条件： | -20度保存 |
| 规格： | 5mg/10mg/50mg |
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医诺生物提供生物医学研究中最常用的八十余种小分子药物，国际质量，国内价格，欢迎选购！如遇质量问题，全额退款！
| 产品标号 | 化合物 | CAS 号 | 结构图 | 说明 | 规格和价格 |
| EI-SM-076 | A66 | 1166227-08-2 |  | a potent and specific p110α inhibitor with IC50 of 32 nM. | 规格：5mg 10mg 50mg 价格: ￥1120 ￥2100 ￥6360 |
| EI-SM-042 | ABT-263 (Navitoclax) | 923564-51-6 | | a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM, and ≤1 nM, respectively. | 规格：5mg 10mg 25mg 价格: ￥790 ￥1310 ￥2430
|
| EI-SM-031 | AC480 (BMS-599626) | 714971-09-2 | | a selective and potent inhibitor of HER1 and HER2 with IC50 of 20 nM and 30 nM respectively. | 规格：5mg 25mg 价格: ￥1120 ￥3740 |
| EI-SM-030 | Afatinib (BIBW2992) | 439081-18-2 | | irreversibly inhibits EGFR/HER2 including EGFR(wt), EGFR(L858R), EGFR(L858R/T790M) and HER2 with IC50 of 0.5 nM, 0.4 nM, 10 nM and 14 nM, respectively. | 规格：5mg 10mg 价格: ￥660 ￥1180 |
| EI-SM-039 | Alectinib (CH5424802) | 1256580-46-7 | | a potent ALK inhibitor with IC50 of 1.9 nM, sensitive to L1196M mutation. | 规格：5mg 10mg 50m 价格: ￥1120 ￥1770 ￥5050 |
| EI-SM-082 | Alisertib (MLN8237) | 1028486-01-2 | | a selective Aurora A inhibitor with IC50 of 1.2 nM. | 规格：5mg 10mg 50mg 价格: ￥790 ￥1380 ￥4400 |
| EI-SM-064 | Azacitidine | 320-67-2 | | specifically inhibits DNA methylation by trapping DNA methyltransferases. | 规格：50mg 价格: ￥640 |
| EI-SM-077 | BEZ235(NVP-BEZ235) | 915019-65-7 | | a dual ATP-competitive PI3K and mTOR inhibitor for p110α/γ/δ/β and mTOR(p70S6K) with IC50 of 4 nM /5 nM /7 nM /75 nM /6 nM, respectively. Inhibits ATR with IC50 of 21 nM. | 规格：50mg 100mg 价格: ￥720 ￥1120 |
| EI-SM-078 | BKM120 (NVP-BKM120, Buparlisib) | 944396-07-0 | | a selective PI3K inhibitor of p110α/β/δ/γ with IC50 of 52 nM/166 nM/116 nM/262 nM, respectively. | 规格：5mg 10mg 价格: ￥1120 ￥1970 |
| EI-SM-054 | Bortezomib (PS-341) | 179324-69-7 | | a potent 20S proteasome inhibitor with Ki of 0.6 nM. | 规格：5mg 25mg 价格: ￥460 ￥1770 |
| EI-SM-023 | BIO | 667463-62-9 | | a specific inhibitor of GSK-3α/β with IC50 of 5 nM, which activates Wnt signaling pathway. | 规格：10mg 50mg 价格: ￥970 ￥3740 |
| EI-SM-036 | Cabozantinib (XL184, BMS-907351) | 849217-68-1 | | a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively. | 规格：5mg 10mg 50mg 价格: ￥720 ￥1120 ￥3080 |
| EI-SM-079 | CAL-101 (Idelalisib, GS-1101) | 870281-82-6 | | a selective p110δ inhibitor with IC50 of 2.5 nM. | 规格：10mg 50mg 价格: ￥790 ￥3080 |
| EI-SM-056 | Carfilzomib(PR171) | 868540-17-4 | | an irreversible proteasome inhibitor with IC50 of <5 nM. | 规格：5mg 10mg 50mg 价格: ￥1120 ￥1770 ￥4400 |
| EI-SM-040 | Ceritinib (LDK378) | 1032900-25-6 | | a potent inhibitor against ALK with IC50 of 0.2 nM. | 规格：5mg 50mg 价格: ￥970 ￥3080
|
| EI-SM-002 | CHIR99021 | 252917-06-9 | | a potent, ATP-competitive & highly selective GSK-3 inhibitor, which inhibits GSK-3α and GSK-3β with IC50 of 10 nM and 6.7 nM, respectively | 规格：2mg 5mg 25mg 价格: ￥590 ￥1120 ￥3740 |
| EI-SM-034 | Crizotinib (PF2341066） | 877399-52-5 | | a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM, respectively. | 规格：5mg 10mg 50mg 价格: ￥720 ￥1120 ￥3740 |
| EI-SM-069 | Dabrafenib（GSK2118436) | 1195765-45-7 | | a mutant BRAFV600 specific inhibitor with IC50 of 0.8 nM, with 4- and 6-fold less potency against B-Raf(wt) and c-Raf, respectively. | 规格：5mg 10mg 20mg 价格: ￥590 ￥850 ￥1120
|
| EI-SM-057 | DAPT (GSI-IX) | 208255-80-5 | | an inhibitor of γ-secretase and Notch, a γ-secretase substrate | 规格：5mg 10mg 25mg 价格: ￥460 ￥790 ￥1380
|
| EI-SM-038 | Dasatinib | 302962-49-8 | | a novel, potent and multi-targeted inhibitor of Abl, Src and c-Kit, with IC50 of <1 nM, 0.8 nM and 79 nM, respectively. | 规格：25mg 价格: ￥240 |
| EI-SM-063 | Decitabine | 2353-33-5 | | a potent inhibitor of DNA methylation. | 规格：10mg 25mg 50mg 价格: ￥590 ￥1120 ￥2100 |
| EI-SM-025 | Dorsomorphin 2HCl | 1219168-18-9 | | a potent and selective inhibitor of ATR kinase with IC50 of 5 nM | 规格：10mg 50mg 价格: ￥970 ￥3080 |
| EI-SM-074 | Doxorubicin (Adriamycin) | 25316-40-9 | | an antibiotic agent and a DNA intercalator that inhibits DNA topoisomerase II and induces DNA damage and apoptosis in tumor cells | 规格：10mg 25mg 价格: ￥590 ￥1380 |
| EI-SM-021 | Everolimus (RAD001) | 159351-69-6 | | an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM. | 规格：10mg 25mg 价格: ￥720 ￥1380 |
| EI-SM-028 | Erlotinib HCl (OSI-744) | 183321-74-6 | | an EGFR inhibitor with IC50 of 2 nM. | 规格：100mg 500mg 价格: ￥970 ￥2430
|
| EI-SM-050 | Fludarabine | 21679-14-1 | | a STAT1 activation inhibitor and a DNA synthesis inhibitor. | 规格：5mg 10mg 25mg 价格: ￥330 ￥640 ￥1250 |
| EI-SM-011 | GDC0941 | 957054-30-7 | | a potent inhibitor of PI3Kα/δ with IC50 of 3 nM | 规格：5mg 10mg 50mg 价格: ￥790 ￥1120 ￥2430 |
| EI-SM-018 | Gefitinib | 184475-35-2 | | an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively | 规格：100mg 250mg 价格: ￥330 ￥660 |
| EI-SM-032 | Imatinib (STI571) | 152459-95-5 | | a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively | 规格：250mg 500mg 价格: ￥460 ￥790 |
| EI-SM-001 | IWR-1-endo | 1127442-82-3 | | a Wnt/β-catenin inhibitor with an IC50 value of 180 nM. | 规格：5mg 10mg 价格: ￥460 ￥720 |
| EI-SM-010 | （+）-JQ-1 | 1268524-70-4 | | a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4(1/2) | 规格：10mg 25mg 价格: ￥1770 ￥3740 |
| EI-SM-029 | Lapatinib | 231277-92-2 | | a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively. | 规格：25mg 100mg 价格: ￥720 ￥1770 |
| EI-SM-003 | LDN193189 | 1062368-24-4 | | a selective BMP signaling inhibitor,with IC50 of 5 nM and 30 nM for inhibition of the BMP type I receptors ALK2 and ALK3, respectively | 规格：2mg 5mg 价格: ￥720 ￥1050 |
| EI-SM-044 | Lenalidomide (CC-5013) | 191732-72-6 | | a TNF-α secretion inhibitor with IC50 of 13 nM. | 格：10mg 价格: ￥250 |
| EI-SM-007 | LY2157299 | 700874-72-2 | | a potent TGFβ receptor I (TβRI) inhibitor with IC50 of 56 nM | 规格：5mg 10mg 价格: ￥1120 ￥1770 |
| EI-SM-012 | LY411575 | 209984-57-6 | | a potent γ-secretase inhibitor with IC50 of 0.082 nM, which inhibits Notch cleavage with IC50 of 0.39nM | 规格：10mg 50mg 价格: ￥1210 ￥3940 |
| EI-SM-017 | LY294002 | 154447-36-6 | | an inhibitor of PI3Kα/δ/β with IC50 of 0.5 μM/0.57 μM/0.97 μM respectively | 规格：10mg 25mg 价格: ￥970 ￥1770 |
| EI-SM-055 | MG132 | 133407-82-6 | | an inhibitor of proteasome with IC50 of 100 nM in a cell-free assay, and also inhibits calpain with IC50 of 1.2 μM. | 规格：5mg 25mg 100mg 价格: ￥330 ￥1120 ￥3080 |
| EI-SM-086 | Mitomycin C | 50-07-7 | | an antineoplastic antibiotic by inhibiting DNA synthesis. | 规格：10mg 50mg 200mg 价格: ￥640 ￥1950 ￥3920 |
| EI-SM-051 | MK2206 | 1032350-13-2 | | a highly selective inhibitor of Akt1/2/3 with IC50 of 8 nM/12 nM/65 nM. | 规格：5mg 10mg 25mg 价格: ￥720 ￥1120 ￥2430
|
| EI-SM-061 | ML324 | 1222800-79-4 | | a selective inhibitor of jumonji histone demethylase (JMJD2) with IC50 of 920 nM. | 规格：10mg 50mg 价格: ￥640 ￥2080 |
| EI-SM-052 | Nilotinib (AMN-107) | 641571-10-0 | | a Bcr-Abl inhibitor with IC50<30 nM. | 规格：25mg 100mg 价格: ￥460 ￥1380 |
| EI-SM-033 | Nintedanib (BIBF 1120) | 928326-83-4 | | a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/β with IC50 of 34 nM/13 nM/13 nM, 69 nM/37 nM/108 nM and 59 nM/65 nM respectively. | 规格：5mg 10mg 50mg 价格: ￥790 ￥1380 ￥4400 |
| EI-SM-013 | NUTLIN 3 | 890090-75-2 | | a potent and selective Mdm2 (a ubiquitin protein ligase for p53) antagonist with IC50 of 90 nM | 规格：5mg 10mg 25mg 价格: ￥720 ￥1120 ￥2430 |
| EI-SM-060 | Olaparib (AZD2281, KU0059436) | 763113-22-0 | | a selective inhibitor of PARP1/2 with IC50 of 5 nM/1 nM. | 规格：10mg 25mg 100mg 价格: ￥460 ￥980 ￥2430 |
| EI-SM-053 | Paclitaxel | 33069-62-4 | | a chemo drug and a microtubule polymer stabilizer with IC50 of 0.1 pM | 规格：10mg 50mg 价格: ￥460 ￥1770 |
| EI-SM-072 | Palbociclib (PD-0332991) HCl | 827022-32-2 | | a highly selective inhibitor of CDK4/6 with IC50 of 11 nM/16 nM, respectively. | 规格：5mg 10mg 价格: ￥720 ￥1120 |
| EI-SM-059 | Panobinostat (LBH589) | 404950-80-7 | | a broad-spectrum HDAC inhibitor with IC50 of 5 nM. | 规格：10mg 50mg 价格: ￥590 ￥1770
|
| EI-SM-080 | Pazopanib | 444731-52-6 | | a multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM, respectively. | 规格：25mg 100mg 价格: ￥460 ￥1380 |
| EI-SM-083 | PD-1/PD-L1 inhibitor 1 | 1675201-83-8 | | disrupts PD-1/PDL-1 interaction. | 规格：5mg 25mg 价格: ￥970 ￥3260 |
| EI-SM-014 | PD0325901 | 391210-10-9 | | a selective and non ATP-competitive MEK inhibitor with IC50 of 0.33 nM | 规格：5mg 25mg 价格: ￥460 ￥1770 |
| EI-SM-015 | PD173074 | 219580-11-7 | | a potent FGFR1 inhibitor with IC50 of ~25 nM, which also inhibits VEGFR2 with IC50 of 100-200 nM | 规格：5mg 10mg 价格: ￥460 ￥790 |
| EI-SM-067 | PD98059 | 167869-21-8 | | a non-ATP competitive MEK inhibitor with IC50 of 2 μM. | 规格：5mg 10mg 价格: ￥540 ￥970 |
| EI-SM-073 | Pemetrexed | 150399-23-8 | | an antifolate and antimetabolite for TS, DHFR and GARFT with Ki of 1.3 nM, 7.2 nM and 65 nM, respectively. | 规格：10mg 50mg 价格: ￥790 ￥3080 |
| EI-SM-019 | Rapamycin（sirolimus ） | 53123-88-9 | | a specific mTOR inhibitor with IC50 of ~0.1 nM | 规格：5mg 25mg 价格: ￥460 ￥1770 |
| EI-SM-047 | Regorafenib（BAY73-4506） | 755037-03-7 | | a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively. | 规格：25mg 价格: ￥1570 |
| EI-SM-016 | RG108 | 48208-26-0 | | DNA methyltransferase Inhibitor with IC50 of 115 nM | 规格：10mg 50mg 价格: ￥750 ￥3140 |
| EI-SM-043 | RITA (NSC 652287) | 213261-59-7 | | induces DNA-protein and DNA-DNA cross-links with no detectable DNA single-strand breaks, and also inhibits MDM2-p53 interaction by targeting p53. | 规格：5mg 10mg 价格: ￥1120 ￥1770 |
| EI-SM-006 | SAG | 912545-86-9 | | A potent agonist of Hedgehog (Hh)/Smoothened(Smo) signalling with EC50 of 3nM | 规格：2mg 5mg 价格: ￥770 ￥1620 |
| EI-SM-070 | SB203580 | 152121-47-6 | | a p38 MAPK inhibitor with IC50 of 0.3-0.5 μM, 10-fold less sensitive to SAPK3(106T) and SAPK4(106T) and it blocks PKB phosphorylation with IC50 of 3-5 μM. | 规格：25mg 50mg 100mg 价格: ￥970 ￥1770 ￥2430 |
| EI-SM-004 | SB431542 | 301836-41-9 | | a potent and selective inhibitor of ALK5 with IC50 of 94 nM | 规格：10mg 50mg 价格: ￥940 ￥3080 |
| EI-SM-026 | Sorafenib Tosylate | 284461-73-0 | | a multikinase inhibitor of Raf-1, B-Raf and VEGFR-2 with IC50 of 6 nM, 22 nM and 90 nM, respectively | 规格：5mg 10mg 50mg 价格: ￥970 ￥1440 ￥4400 |
| EI-SM-071 | SP600125 | 129-56-6 | | a broad-spectrum JNK inhibitor for JNK1, JNK2 and JNK3 with IC50 of 40 nM, 40 nM and 90 nM, respectively. | 规格：10mg 50mg 价格: ￥420 ￥1620 |
| EI-SM-027 | Sunitinib Malate | 341031-54-7 | | a multi-targeted RTK inhibitor targeting VEGFR2 (Flk-1) and PDGFRβ with IC50 of 80 nM and 2 nM, which also inhibits c-Kit. | 规格：100mg 价格: ￥970 |
| EI-SM-037 | SSR128129E | 848318-25-2 | | an allosteric and selective FGFR1 inhibitor with IC50 of 1.9 μM. | 规格：5mg 20mg 价格: ￥640 ￥1770
|
| EI-SM-022 | Tacrolimus (FK506） | 104987-11-3 | | binds to the immunophilin FKBP12; inhibits PP2B (calcineurin); reduces peptidyl-prolyl isomerase activity in T cells. | 规格：50mg 100mg 价格: ￥590 ￥1120 |
| EI-SM-045 | Thalidomide | 50-35-1 | | Thalidomide inhibits an E3 ubiquitin ligase in CRBN-DDB1-Cul4A complex. It inhibits TNF α biosynthesis and bFGF-induced angiogenesis. It also induces apoptosis in human monocyte cultures, and suggested to inhibit HIV-1 replication. | 规格：200mg 价格: ￥530 |
| EI-SM-049 | Tofacitinib citrate(CP690550) | 540737-29-9 | | a potent and selective inhibitor of JAK3 with IC50 of 1 nM. | 规格：5mg 25mg 价格: ￥390 ￥1350 |
| EI-SM-065 | Trametinib (GSK1120212) | 871700-17-3 | | a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM. | 规格：5mg 10mg 价格: ￥660 ￥980 |
| EI-SM-066 | U0126-EtOH | 1173097-76-1 | | a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM. | 规格：25mg 100mg 价格: ￥970 ￥3080 |
| EI-SM-068 | Vemurafenib (PLX4032, RG7204) | 918504-65-1 | | a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM. | 规格：10mg 50mg 价格: ￥460 ￥1770 |
| EI-SM-041 | Venetoclax (ABT-199, GDC-0199) | 1257044-40-8 | | a Bcl-2-selective inhibitor with Ki of <0.01 nM. | 规格：5mg 50mg 价格: ￥1770 ￥6360 |
| EI-SM-008 | Vismodegib(GDC0449) | 879085-55-9 | | a potent and specific inhibitor of Hedgehog (Hh)/Smoothened(Smo) signaling with IC50 of 3nM | 规格：5mg 10mg 价格: ￥590 ￥1390 |
| EI-SM-058 | Vorinostat (suberoylanilide hydroxamic acid, SAHA) | 149647-78-9 | | an HDAC inhibitor with IC50 of ~10 nM. | 规格：200mg 500mg 价格: ￥970 ￥1440 |
| EI-SM-081 | XAV-939 | 284028-89-3 | | a selective inhibitor of Wnt/β-catenin signaling through tankyrase1/2 inhibition with IC50 of 11 nM/4 nM. | 规格：10mg 25mg 50mg 价格: ￥460 ￥1120 ￥1770 |
| EI-SM-005 | Y27632 2hcl | 129830-38-2 | | a selective Rho-kinase inhibitor | 规格：2mg 5mg 10mg 价格: ￥460 ￥790 ￥1120 |
| EI-SM-046 | YM155 | 781661-94-7 | | a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0.54 nM, also slightly inhibits the interaction of Survivin with XIAP. | 规格：5mg 10mg 25mg 价格: ￥460 ￥790 ￥1770 |
| EI-SM-020 | ZSTK-474 | 475110-96-4 | | an inhibitor of class I PI3K isoforms, mostly PI3Kδ, with IC50 of 37 nM | 规格：10mg 50mg 价格: ￥460 ￥1770 |
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