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| 货号： | K149-100 |
| 保存条件： | -20度 |
| 供应商： | 北京博迈斯 |
| 英文名： | Cathepsin S Inhibitor Screening Kit (Fluorometric) |
| 规格： | 100 assays |
Assay Kit Name:
Cathepsin S Inhibitor Screening Kit (Fluorometric)
Kit Summary:
• Detection method - Fluorescence (Ex/Em = 400/505 nm)
• Applications - Screen/study/characterize potential inhibitors of Cathepsin S.
Features & Benefits:
• Simple & convenient
• High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin S
• Cathepsin S inhibitor, Z-FF-FMK is included in the kit
Kit Components:
• CTSS Reaction Buffer
• Cathepsin S (human)
• CTSS Substrate, Z-VVR-AFC (10 mM)
• CTSS Inhibitor (Z-FF-FMK, 1 mM)
Description:
Cathepsin S (CTSS, EC 3.4.22.27) is a lysosomal cysteine proteinase that is suggested to participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Biovision’s Cathepsin S Inhibitor Screening Kit utilizes the ability of Cathepsin S to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin S inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This high-throughput adaptable assay kit is simple, sensitive, and rapid tool to screen the potential inhibitors of Cathepsin S.
Storage Conditions:
-20°C
Shipping Conditions:
gel pack
USAGE: For Research Use Only! Not For Use in Humans.
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