组织蛋白酶S抑制剂筛选试剂盒(荧光法)

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单价: 6675.00
品牌: biovsion
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更新: 2021-04-21
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货号: K149-100
保存条件: -20度
供应商: 北京博迈斯
英文名: Cathepsin S Inhibitor Screening Kit (Fluorometric)
规格: 100 assays

Assay Kit Name:
Cathepsin S Inhibitor Screening Kit (Fluorometric)

Kit Summary:
• Detection method - Fluorescence (Ex/Em = 400/505 nm)
• Applications - Screen/study/characterize potential inhibitors of Cathepsin S.

Features & Benefits:
• Simple & convenient
• High-throughput adaptable assay to screen/study/characterize the potential inhibitors of Cathepsin S
• Cathepsin S inhibitor, Z-FF-FMK is included in the kit

Kit Components:
• CTSS Reaction Buffer
• Cathepsin S (human)
• CTSS Substrate, Z-VVR-AFC (10 mM)
• CTSS Inhibitor (Z-FF-FMK, 1 mM)

Description:
Cathepsin S (CTSS, EC 3.4.22.27) is a lysosomal cysteine proteinase that is suggested to participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. Biovision’s Cathepsin S Inhibitor Screening Kit utilizes the ability of Cathepsin S to cleave the synthetic AFC based peptide substrate to release AFC, which can be easily quantified using a fluorometer or fluorescence microplate reader. In the presence of a Cathepsin S inhibitor, the cleavage of the substrate is reduced/abolished resulting in decrease or total loss of the AFC fluorescence. This high-throughput adaptable assay kit is simple, sensitive, and rapid tool to screen the potential inhibitors of Cathepsin S.

Storage Conditions:
-20°C

Shipping Conditions:
gel pack

USAGE: For Research Use Only! Not For Use in Humans.

温馨提示:不可用于临床治疗。