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份 库存999份
| 货号： | ab120026 |
| CAS号： | 6104-71-8 |
| 英文名： | N-Desmethyl clozapine (Normethylclozapine) |
| 保质期： | 12个月 |
| 保存条件： | +4°C 干燥 |
| 规格： | 10 mg |
概述
- 产品名称
N-Desmethyl clozapine (Normethylclozapine) - 描述
Clozapine metabolite. M1 agonist. D2/D3 agonist. - 别名
- Normethylclozapine
- 生物学描述
Brain penetrant metabolite of the atypical antipsychotic clozapine. Broad range of actions. Potent allosteric M1 partial agonist (IC50 = 55 nM for inhibition of [3H]-NMS binding). D2/D3 partial agonist. Also displays affinity at 5-HT1 and 5-HT2. - 纯度
> 99%
性能
- 化学名称
8-Chloro-11-(1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine - 分子量
312.80 - 化学结构
- 分子式
C17H17ClN4 - CAS编号
6104-71-8 - PubChem识别号
2820 - 存放说明
Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. - 溶解度概述
Soluble in DMSO to 100 mM - 处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- SMILES
Clc1ccc2Nc4ccccc4C(=Nc2c1)N3CCNCC3 - 来源
Synthetic
温馨提示：不可用于临床治疗。
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