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份 库存999份
| 货号： | ab120374 |
| CAS号： | 125314-64-9 |
| 英文名： | Ro 31-8220 mesylate (Bisindolylmaleimide IX) |
| 保质期： | 12 months |
| 保存条件： | Store at -20°C |
| 规格： | 1 mg |
概述
- 产品名称
Ro 31-8220 mesylate (Bisindolylmaleimide IX) - 描述
Protein kinase inhibitor - 别名
- Bisindolylmaleimide IX
- 生物学描述
Widely used as a cell-permeable, reversible, competitive protein kinase C inhibitor. Also potently inhibits wide range of kinases inlcuding RSK1, RSK2, PRK2, PKCα, PKD1, MSK1, GSK3β, CDK2-cyclin A and PIM3, as well as PKCα.
Also available in simple stock solutions (ab146723) - add 1 ml of water to get an exact, ready-to-use concentration. - 纯度
> 98%
性能
- 化学名称
3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methyl-3-indolyl)-1H-pyrrole-2,5-dione methanesulfonate - 分子量
553.65 - 化学结构
- 分子式
C25H23N5O2S.CH3SO3H - CAS编号
125314-64-9 - PubChem识别号
11628205 - 存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. - 溶解度概述
Soluble in water to 100 mM, DMSO to 100 mM and in ethanol to 5 mM - 处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- SMILES
CS(=O)(=O)O.Cn2cc(c1ccccc12)C=5C(=O)NC(=O)C=5c4cn(CCCSC(=N)N)c3ccccc34 - 来源
Synthetic
温馨提示：不可用于临床治疗。
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