货号: | ab120542 |
CAS号: | 11032-79-4 |
英文名: | α-Bungarotoxin |
保质期: | 12个月 |
保存条件: | -20°C 干燥 |
规格: | 1 mg |
概述
- 产品名称
α-Bungarotoxin - 描述
Subtype-selective α7 nAChR antagonist - 生物学描述
Irreversible antagonist of nicotinic acethylcholine receptors (nAChRs). 74-aa polypeptide derived from the venom of the banded krait, Bungarus multicinctus. Selective for α7 receptors over α3β4 receptors (IC50 values are 1.6 nM and >3 μM, respectively). Blocks neuromuscular transmission. Inhibits opening of nicotinic receptor-associated ion channels.
性能
- 分子量
7984.14 - 化学结构
- 分子式
C338H529N97O105S11 - CAS编号
11032-79-4 - 序列
IVCHTTATSPISAVTCPPGENLCYRKMWCDAFCSSRGKVVELGCAATCPSKKPYEEVTCCSTDKCNPHPKQRPG (Modifications: Disulfide bonds: 3-23, 16-44, 29-33, 48-59, 60-65) - PubChem识别号
44264212 - 存放说明
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. - 溶解度概述
Soluble in any aqueous buffer. It is recommended that all preparations are centrifuged before use. - 处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- 来源
Bungarus multicinctus
温馨提示:不可用于临床治疗。