| 英文名称 | Rabbit EIF4G1 Polyclonal Antibody |
| 别名 | EIF-4G1;EIF4F;EIF4G;EIF4GI;P220;PARK18 |
| 应用 | WB,IHC,IF |
| 稀释比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:200 |
| 交叉反应 | Human |
| 蛋白分子量 | 175kDa |
| Gene ID | 1981 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | A synthetic peptide of human EIF4G1 |
| 性状 | Lyophilized or Liquid |
| Swiss Prot | Q04637 |
| 克隆类型 | Polyclonal Antibody |
| 来源 | Rabbit |
| 背景资料 | The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. |
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