| 英文名称 | Rabbit PSMD8 Polyclonal Antibody |
| 别名 | HEL-S-91n;HIP6;HYPF;Nin1p;Rpn12;S14;p31 |
| 应用 | WB,IHC,IF |
| 稀释比例 | WB1:500-1:2000 IHC1:50-1:200 IF1:50-1:100 |
| 交叉反应 | Human,Mouse,Rat |
| 蛋白分子量 | 40kDa |
| Gene ID | 5714 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles.Stable for one year from the date of shipment. |
| 储存液 | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 纯化方法 | Affinity purification |
| 亚型 | IgG |
| 免疫原 | Recombinant protein of human PSMD8 |
| 性状 | Lyophilized or Liquid |
| Swiss Prot | P48556 |
| 克隆类型 | Polyclonal Antibody |
| 来源 | Rabbit |
| 背景资料 | The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 1. |
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