货号：	IRKTAH5381
供应商：	上海钰博生物科技有限公司
数量：	大量
英文名：	Mouse IL15RA ELISA Kit
保质期：	1年
保存条件：	-2-8℃
规格：	盒

Mouse IL15RA ELISA Kit

Product Description

Mouse IL15RA ELISA Kit - 1 Kit (96 Wells)

Our Mouse IL15RA ELISA Kit is a sandwich ELISA intended for the quantitative determination of mouse IL15RA in cell culture supernates, serum and plasma (heparin, EDTA).

Interleukin 15 receptor, alpha subunit is a subunit of the interleukin 15 receptor which is encoded by the gene IL15RA in humans. The human IL15RA gene was mapped to chromosome 10p15-p14 by FISH and the mouse Il15ra gene was mapped to chromosome 2. The cytoplasmic domain of IL15R-alpha, like that of IL2R-alpha, was dispensable for mitogenic signaling, suggesting that the primary role of the alpha chains is to confer high-affinity binding. At high concentrations, IL15, like IL2, was able to signal through a complex of IL2R-beta and -gamma in the absence of the alpha subunit. The soluble receptor displayed high affinity for IL15 and inhibited both binding of IL15 to the membrane receptor and IL15-induced cell proliferation.