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| 货号： | F70101C-N |
| CAS号： | 22560-50-5 |
| 供应商： | 上海伟进生物科技有限公司 |
| 数量： | 现货 |
| 英文名： | Clophosome®- Clodronate Liposomes (Neutral) |
| 保质期： | 6个月 |
| 保存条件： | 4℃ |
| 规格： | 2ml/10ml |
Product Description
Clophosome®- Clodronate Liposomes (Neutral)
Clophosome®, neutral clodronate liposomes, offers highly efficient in vivo macrophage depletion. Clodronate molecules are encapsulated in small MLV liposomes for superior activity, physical and chemical stability, and convenience of use. It is formulated to an exceptionally high clodronate/lipid ratio. Free clodronate is cleaned out and the liposomal clodronate encapsulation efficiency is more than 90%. Clophosome liposomes remain homogenous and suspended even after long term storage in fridge. It is not viscous and easy to inject. It is manufactured sterile for long term shelf-life.
The product is suitable for dosing with various routes including intravenous, intraperitoneal, subcutaneous, intranasal, intratracheal and etc. We have achieved 80-90% macrophage depletion in spleen (red pulp macrophages) 24 hours after a single 0.2 mL intravenous injection. A starting dose of 0.15 - 0.2 mL (i.v. or i.p.) for 20-25g animal body weight is recommended for good consistency in macrophage depletion. Optimization is recommended for your specific applications.
Specifications
Product code: F70101C-N
Brand Name: Clophosome®
Active: clodronate disodium. CAS: 22560-50-5, 7 mg/mL
Lipid composition: phosphatidylcholine and cholesterol
Bulk solution: phosphate buffered sucrose (20mM sodium phosphate, 10 % sucrose), pH 7.0-7.5
Shelf-life: 6 months guaranteed for unopened vials
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