P-JAK2（Tyr1007/1008）_抗体制备_免疫学服务_技术服务库_商城

本公司所有一抗，50μl(>50μg)现价450元/支，全部现货，均提供20μl免费试用装，详情请点击免费试用

产品货号	WL02997
产品名称	P-JAK2(Tyr1007/1008) Antibody
预测分子量	Predicted band size: 128 kDa Observed band size: 100 kDa
别名	P-JTK10; P-THCYT3
浓度	＞1 mg/ml
免疫原	合成P-JAK2（Tyr1007/1008)多肽
抗体来源	兔
特异性	抗人、小鼠、大鼠
克隆类型	多克隆抗体
产品应用	WB
成分	亲和纯化抗体，20 mM PBS，150 mM NaCl，100 μg/ml BSA，50%甘油，NaN₃<0.02%
保存条件	-20℃保存
背景资料	Members of the Janus family of tyrosine kinases (JAK1, JAK2, JAK3, and Tyk2) are activated by ligands binding to a number of associated cytokine receptors. Upon cytokine receptor activation, JAK proteins become autophosphorylated and phosphorylate their associated receptors to provide multiple binding sites for signaling proteins. JAK2 is autophosphorylated at Tyr1007/1008 in the putative activation loop during cytokine signaling. Tyr221 and 570 have also been shown to be prominent sites for autophosphorylation. In addition, Tyr813 was identified as a site for autophosphorylation critical for the activation of JAK2 by the SH2 domain-containing protein SH2-B β.

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温馨提示：不可用于临床治疗。

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