货号: | WL01927 |
抗体名: | Caspase-3 抗体 |
抗体英文名: | Caspase-3 Antibody |
浓度: | >1mg/ml |
应用范围: | WB |
宿主: | 兔 |
适应物种: | M,R |
标记物: | 无 |
克隆性: | 否 |
保存条件: | -20℃ |
形态: | 液体 |
亚型: | IgG |
规格: | 50μl(>50μg) |
本公司所有一抗,50μl(>50μg)现价450元/支,全部现货,均提供20μl免费试用装,详情请点击免费试用
产品货号 | WL01927 | |||
产品名称 | Caspase-3 Antibody | |||
预测分子量 | 32kDa | |||
别名 | CASP3; CPP32; CPP32B; SCA-1 | |||
浓度 | >1 mg/ml | |||
免疫原 | 合成Caspase-3多肽 | |||
抗体来源 | 兔 | |||
特异性 | 抗小鼠,大鼠 | |||
克隆类型 | 多克隆抗体 | |||
产品应用 | WB | |||
成分 | 亲和纯化抗体,20 mM PBS,150 mM NaCl,100 μg/ml BSA,50%甘油,NaN3<0.02% | |||
保存条件 | -20℃保存 | |||
背景资料 | This Caspase-3 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. Caspase-3 is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins, such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP). | |||
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