【求助】关于慢病毒的RNA聚合酶..._RNA聚合酶_核酸酶类_分子类_知道

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游客	收藏 \| 举报 2009-09-24 17:03 关注：215 回答：1 【求助】关于慢病毒的RNA聚合酶... 已解决悬赏分：0 - 解决时间 2024-12-22 00:36 【求助】关于慢病毒的RNA聚合酶

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举报 2009-10-02 09:58

Lentivirus, such as HIV-1 infects human CD4 plus cells. In the infected cells, HIV-1 reverse transcriptase performs viral cDNA synthesis using HIV-1 RNA genome as template. The double-stranded viral cDNA is then integrated into host cellular genome catalyzed by HIV-1 integrase. The integrated HIV-1 cDNA is called provirus, and the proviral DNA is transcribed into viral RNA by cellular RNA polymerases. Therefore, HIV-1 RNA polymerase major functions are different from that of cellular ones.