Multiple Alignment Construction & Analysis Workbench (MACAW) is a program for locating, analyzing, and editing blocks of localized sequence similarity among multiple sequences and linking them into a multiple alignment. It includes sequence alignment search, editing and display. It is a very nice program according to many, allowing one to look for blocks of homology in sequences.
MACAW(Multiple Alignment Construction and Analysis Workbench)可以使用户通过定位,分析,编辑及将比对序列片段联合成块)来构建多重比对.
MACAW整合了几个新特性:
(1)使用新的搜索算法来定位局部相似区域,这避免了以前的技术所带来的许多限制;
(2)使用最新发展的数学理论来评估块相似性的统计学意义;
(3)使用多种 可视化工具对候选块进行评估以预测其包含于多重序列比对中的潜在可能性;
(4)有一个用户界面允许用户对块进行逐个编,用户可以移 动块边界,剔除特定片段或将块链 接起来以形成复合多重比对.
MACAW将可变编辑,分析 及显示工具同一个简单但是强大的算法整合在一起,从而将比对分解成易解决的问题.