This free software enables you to design high quality PCR primers for methylation mapping experiments. Simply cut and paste in your region of interest. The tool searches for CpG islands and simulates bisulfite modification of DNA in silico. Applied Biosystems supplies all the tools you need to complete methylation mapping experiments.
本软件主要作用是辅助设计出具有甲基化 (methylation)或硫化 (bisulphite)的特殊聚合酶链锁反应的引物(primers) 。在进行DNA甲基化分析的研究过程中,许多研究人员认为最麻烦也是最花时间的过程,就属设计出具有专一性辨识能力的特异核酸引物,这一套软件可以在短短五分钟之内,设计出合用的核酸引物。